Bioactive Small Molecules
A vast array of small, non-peptide, organic compounds that are biologically active. Products include receptor antagonists, molecular probes, metabolites, GPCR ligands, neurotransmitters, ion channel modulators, and signaling activators and inhibitors.
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931
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945
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931
Tocris Bioscience™ NKY 80
Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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CAS: 299442-43-6 Molecular Formula: C12H11N3O2
| CAS | 299442-43-6 |
|---|---|
| Molecular Formula | C12H11N3O2 |
932
Tocris Bioscience™ NAV 2729
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Selective ARF6 inhibitor
| CAS | 419547-11-8 |
|---|---|
| Product Type | Inhibitor |
| Color | Yellow |
| Solubility | Soluble to 100mM in DMSO |
| Recommended Storage | Store at 4°C |
| Molecular Formula | C25H17ClN4O3 |
| Formula Weight | 456.88g/mol |
933
Tocris Bioscience™ Obatoclax Mesylate
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Inhibitor of Bcl-2 family members (IC50 values are 1.11 - 7 μM); antiapoptotic
| CAS | 803712-79-0 |
|---|---|
| Purity | 98% |
| Chemical Name or Material | 2-[2-[(3,5-Dimethyl-1H-pyrrol-2-yl)methylene)-3-methoxy-2H-pyrrol-5-yl]-1H-indole methanesulfonate |
| Recommended Storage | Store at -20°C |
| Synonym | GX15-070 |
| Molecular Formula | C20H19N3O.CH3SO3H |
| Formula Weight | 413.49 |
934
Tocris Bioscience™ MPEP hydrochloride
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Potent mGlu5 antagonist; also positive allosteric modulator of mGlu4 receptors
| Target | Group I mGluR Antagonists |
|---|---|
| CAS | 219911-35-0 |
| Solubility | Soluble to 100mM in DMSO |
| Purity | 99% |
| Chemical Name or Material | 2-Methyl-6-(phenylethynyl)pyridine hydrochloride |
| Recommended Storage | Desiccate at +4°C |
| Molecular Formula | C14H11N.HCl |
| Formula Weight | Observed MW: 229.71 |
| Assay Percent Range | >99% |
935
Tocris Bioscience™ PAG 3'-fluoro-4'-piperazine
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Functionalized cereblon ligand for PROTAC development
936
Tocris Bioscience™ CGP 37849
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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CAS: 127910-31-0 Molecular Formula: C6H12NO5P
| CAS | 127910-31-0 |
|---|---|
| Molecular Formula | C6H12NO5P |
937
Tocris Bioscience™ BIRB 796
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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High affinity and selective p38 kinase inhibitor
| Target | p38 Inhibitors |
|---|---|
| CAS | 285983-48-4 |
| Purity | 0.98 |
| Chemical Name or Material | N-[3-(1,1-Dimethylethyl)-1-(4-methylphenyl)-1H-pyrazol-5-yl]-N′-[4-[2-(4-morpholinyl)ethoxy]-1-naphthalenyl]urea |
| Recommended Storage | Store at -20°C |
| Synonym | Doramapimod |
| Molecular Formula | C31H37N5O3 |
| Formula Weight | 527.66 |
938
Tocris Bioscience™ Phosphocreatine disodium salt
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CAS: 922-32-7 Molecular Formula: C4H8N3Na2O5P
| CAS | 922-32-7 |
|---|---|
| Molecular Formula | C4H8N3Na2O5P |
939
Tocris Bioscience™ A 317491 sodium salt
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Selective, high affinity P2X3 and P2X2/3 antagonist; antinociceptive
| Target | P2X Receptor Antagonists |
|---|---|
| Product Type | Antagonist |
| Purity | 98% |
| Chemical Name or Material | 5-[[[(3-Phenoxyphenyl)methyl][(1 S)-1,2,3,4-tetrahydro-1-naphthalenyl]amino]carbonyl]-1,2,4-benzenetricarboxylic acid disodium salt |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C33H25NO8Na2 |
| Formula Weight | 609.54 |
940
Tocris Bioscience™ Janelia Fluor™ 635, Haloalkane
Cell-permeable fluorogenic fluorescent dye with a chloroalkane handle. Application: live-cell imaging as a self-labeling tag substrate
941
Tocris Bioscience™ GW 803430
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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CAS: 515141-51-2 Molecular Formula: C25H24ClN3O3S
| CAS | 515141-51-2 |
|---|---|
| Molecular Formula | C25H24ClN3O3S |
942
Tocris Bioscience™ Nateglinide
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CAS: 105816-04-4 Molecular Formula: C19H27NO3
| CAS | 105816-04-4 |
|---|---|
| Molecular Formula | C19H27NO3 |
943
Tocris Bioscience™ SCOTfluor 510 Fmoc-Dapa-OH
Fmoc protected fluorescent amino acid for use in solid-phase peptide synthesis to prepare PAINT imaging probes
944
Tocris Bioscience™ CP 43
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Potent TAOK inhibitor
| CAS | 850467-66-2 |
|---|---|
| Purity | 98% |
| Chemical Name or Material | N-(2-Oxo-2-((1,2,3,4-tetrahydronaphthalen-1-yl)amino)ethyl)-[1,1′-biphenyl]-4-carboxamide |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C25H24N2O2 |
945
Tocris Bioscience™ KN 93 phosphate
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CaM kinase II inhibitor; water soluble version of KN 93 (Cat. No. 1278).